Aldosterone Impurity 1 - Names and Identifiers
Name | tetrahydroaldosterone
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Synonyms | tetrahydroaldosterone Aldosterone Impurity 1 3α,5β-Tetrahydroaldosterone 3ALPHA,5B-Tetrahydroaldosterone 5β-Pregnan-11β,18-epoxy-3α,18,21-triol-20-one 11β,18-Epoxy-3α,18,21-trihydroxy-5β-pregnan-20-one Pregnan-20-one, 11,18-epoxy-3,18,21-trihydroxy-, (3α,5β,11β)-
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CAS | 13489-75-3
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Aldosterone Impurity 1 - Physico-chemical Properties
Molecular Formula | C21H32O5
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Molar Mass | 364.48 |
Storage Condition | -20°C |
Aldosterone Impurity 1 - Risk and Safety
Hazard Symbols | Xi - Irritant
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Risk Codes | 43 - May cause sensitization by skin contact
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Safety Description | 36/37 - Wear suitable protective clothing and gloves.
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WGK Germany | 3 |
Aldosterone Impurity 1 - Introduction
Tetrahydroaldosterone (Tetrahydroaldosterone) is a compound with the chemical formula C21H30O5. It is a reduction product of aldosterone, also known as aldosterone condensate. In chemical properties, tetrahydroaldosterone is a white crystalline solid, soluble in alcohol and ether solvents.
tetrahydroaldosterone plays an important physiological role in the body. It is a metabolite. Compared with aldosterone, it has a weaker regulatory effect on renal function. This compound plays an important role in the body's water-electrolyte balance and blood pressure regulation.
Because tetrahydroaldosterone has the activity of inhibiting aldosterone, it has certain application value in the pharmaceutical field. It is used as a precursor to antihypertensive drugs, or as one of the components of antihypertensive drugs.
Usually, tetrahydroaldosterone can be prepared through a series of chemical reactions. For example, aldosterone can be reduced with hydrogen over a catalyst to give tetrahydroaldosterone. The preparation process needs to pay attention to the selection of appropriate solvents and reaction conditions to ensure high yield and purity.
Regarding safety information, there are no clear research results on the toxicity and safety of tetrahydroaldosterone at this stage. Therefore, it is necessary to be cautious when using it and follow relevant experimental operation specifications and safety precautions.
Last Update:2024-04-09 21:04:16